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Case Studies

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Tackling HIV prevention with holistic insights and interventions

Tackling HIV prevention with holistic insights and interventions

Tackling HIV prevention with holistic insights and interventions

How the Bill & Melinda Gates Foundation addressed social, economic, and emotional drivers

How the Bill & Melinda Gates Foundation addressed social, economic, and emotional drivers

higher HIV risk in women

empowerment framework

participants engaged

countries in focus

The challenge

Understanding complex social factors fuelling HIV vulnerability

Adolescent girls and young women in sub-Saharan Africa face disproportionately high HIV risk driven by multiple intertwined factors: economic dependency, social norms, relationship dynamics, and limited prevention uptake. Traditional single-focus interventions struggle to address this nuanced, multifaceted challenge.

Key challenges

  • Lack of context-specific, holistic frameworks

  • Complex motivations behind risky relationships

  • Limited influence of standard prevention programs

  • Intertwined emotional, social and economic pressures

The solution

Crafting holistic frameworks for targeted interventions

Multidimensional research

Qualitative & quantitative

Scenario-based EthnoLab™

Contextualized insights

Tailored frameworks

3x3 empowerment model

5-step relationship journey

Segmentation by motivations

Implementation approach

1

Local engagement

  • Cultural sensitivity

  • Tanzania & South Africa

  • Community interviews

2

Behavioral mapping

  • Self-agency factors

  • Relationship priorities

  • Identifying motivations

3

Iterative refinement

  • Feedback loops

  • Evolving prototypes

  • Partner collaboration

The impact

Empowering person-centered HIV prevention strategies

Deeper understanding

HIV risk for women

  • Complex social drivers

  • Beyond material incentives

  • Tailoring informed interventions

Actionable frameworks

empowerment pillars

  • Bespoke program design

  • Sustainable skill building

  • Emotional, social, economic

Contextual relevance

relationship journey

  • Meeting women’s real goals

  • Aligning prevention & desires

  • Culturally adapted approaches

Looking ahead

Scalable application

  • Adapting novel frameworks regionally

Refined interventions

  • Growing segment-specific programs

Continuous insight

  • Integrating evolving community feedback

All rights reserved © 2025 Fractal Analytics Inc.

Registered Office:

Level 7, Commerz II, International Business Park, Oberoi Garden City,Off. W. E.Highway, Goregaon (E), Mumbai City, Mumbai, Maharashtra, India, 400063

CIN : U72400MH2000PLC125369

GST Number (Maharashtra) : 27AAACF4502D1Z8

All rights reserved © 2025 Fractal Analytics Inc.

Registered Office:

Level 7, Commerz II, International Business Park, Oberoi Garden City,Off. W. E.Highway, Goregaon (E), Mumbai City, Mumbai, Maharashtra, India, 400063

CIN : U72400MH2000PLC125369

GST Number (Maharashtra) : 27AAACF4502D1Z8

All rights reserved © 2025 Fractal Analytics Inc.

Registered Office:

Level 7, Commerz II, International Business Park, Oberoi Garden City,Off. W. E.Highway, Goregaon (E), Mumbai City, Mumbai, Maharashtra, India, 400063

CIN : U72400MH2000PLC125369

GST Number (Maharashtra) : 27AAACF4502D1Z8